Proving the utility of a stably replicating neo-chromosome for engineering pathways in Pichia pastoris

The technology developed in this successful Innovation Fund project could enable Ingenza to identify additional commercial opportunities to expand their current P. pastoris biologics manufacturing platform and attract new commercial end-user partnerships.

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Selection and characterisation of anti-peptide synthetic antibodies for comparison with conventional reagents

This Feasibility funded project developed two antibodies using biopanning of University of Edinburgh’s phage display library, allowing TAC to successfully apply for further funding to advance the project and bringing potentially significant benefits for the Scottish economy.

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Investigating the use of daffodil extracts to treat heart failure

in this project co-funded with the High Value Biorenewables Network, the team successfully developed a process to extract alkaloids from daffodil biomass which could be used in the treatment of heart failure and are now in a position to apply for investment to take the process forward at scale in Scotland.

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Producing broad spectrum antiviral therapeutics from cyanobacteria

In this successful Feasibility Project, the project partners identified antiviral therapeutics that can be extracted from cyanobacteria, and gained leverage for additional funding, training opportunities, and developed new methods for fractionating and purifying polysaccharides.

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Improved paclitaxel yields in a biomanufacturing platform

Innovation funding from IBioIC enabled the project partners to test a new strategy to elucidate the natural production mechanisms used by Taxus brevifolia, also known as the Pacific Yew, and engineer them in faster growing plant cells, and propelled Green Bioactives technology readiness level from 3 to 7.

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Enhancing the purity of speciality seaweed products

Marine Biopolymers (MBL) is a Scottish SME whose focus is on extracting high value components from brown seaweeds for use in a range of applications such as food and pharmaceuticals, but also in different industrial application areas, where the use of natural polymers is growing fast.

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Extending the analytical capability of affordable Microbioreactors

ŌGI Bio Ltd wanted to explore the feasibility of utilising the University of Edinburgh’s state of the art in-line dilution technology to extend the valid range of OD measurements for their microbioreactors.

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Medicine and healthcare Steven Scott Medicine and healthcare Steven Scott

Media Development & Scale-Up of Probiotic Culture Growth to 22 L

Scientists at the University of Bristol discovered a probiotic strain of Streptococcus thermophilus which had been found to have a variety of health benefits. Unfortunately, the media on which it was grown rendered it unsuitable for human consumption. Our Technical Team were approached to develop a new media which would provide similar cell growth and facilitate a commercially viable product.

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