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Multiparameter Sensors and Dissolved Oxygen (DO) Sensor Pills for Shake Flasks: Removing Black Boxes for Improved Bioprocess Development

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Shake flasks are one of the most frequently used bioprocessing vessels. Especially in strain and bioprocess development for screening applications they offer a cost-effective way to achieve the necessary throughputs. However, shake flasks differ significantly from benchtop bioreactors in their design, operation, and size and present black boxes due to a lack of compatible sensor technology.

What is this webinar about?

  • Dr. Christina Dickmeis, a Senior Research Scientist at sbi, presents her work with Pichia pastoris

  • Learn how she achieved a 20-fold increase in protein production in her shake flask cultivation using data collected with the new DOTS Platform

As an attendee, you will learn more about:

  • The new multiparameter sensor (MPS) and dissolved oxygen (DO) sensor pills

  • The use of modern sensors resulted in process optimization in several experiments what took about 200 experiments via manual methods

  • How DO-based feeding resulted in a 20-fold increase in protein production and better comparability to bioreactor runs

This webinar is ideally suited to:

  • Researchers with a focus on microbial bioprocesses and fermentation

  • Researchers focusing on strain development and screening, bioprocess development and optimization as well as scale up

  • Researchers working in shake flasks, bioreactors or other fermentation vessel types

Speaker

Christina Dickmeis

Senior Research ScientistScientific Bioprocessing (sbi)

Christina Dickmeis is a Senior Research Scientist at Scientific Bioprocessing Inc. (sbi) working on the next generation of chemosensors on the R&D Team.

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The Carbon Recycling Network – Fourth Annual Conference

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25 April

Developing innovative processes and technologies for producing biohydrogen for the UK transport sector