FlexBio, Downstream processing, Pharmaceuticals Valerie Evans FlexBio, Downstream processing, Pharmaceuticals Valerie Evans

Biocatalytic Production and Scale-up of 5hmdUMP Purification

This collaboration delivered a tenfold increase in yield for the University of St Andrews, and demonstrated how IBioIC’s facilities and expertise can provide targeted scale-up services to academic partners bridging the gap between laboratory research and preparative bioprocessing.

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Scale-up of Enzyme Production for Cyclodextrin Biomanufacturing

As part of their UKRI Launchpad project for Biomanufacturing in Scotland, NCIMB sought to transition their bench-scale process for producing the enzyme from static flask cultures to a controlled fermentation system suitable for larger-scale enzyme production. To enable this transition, NCIMB subcontracted the fermentation scale-up and enzyme recovery work to the Industrial Biotechnology Innovation Centre (IBioIC), leveraging the FlexBIO facility and technical expertise in bioprocess development and downstream processing.

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