Carbon Negative Construction Materials

This successful project has advanced Ureaka’s ambitions to reduce carbon emissions of cement and concrete production while permanently storing CO2 towards commercialisation.

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How Metabolic Advantages Help Drug-Resistant E. coli Outcompete Gut Bacteria

Research from the Hoskisson Lab at the University of Strathclyde reveals how multidrug-resistant E. coli use metabolic genes on resistance plasmids to outcompete commensal gut bacteria, even without antibiotic pressure.

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Process, materials, Pharmaceuticals Andrew Bonnar Process, materials, Pharmaceuticals Andrew Bonnar

A consolidated bioprocess for one-pot depolymerisation-upcycling of bread waste in engineered bacteria

C-Source Renewables and the University of Edinburgh wanted to explore streamlining the biorefinery/bioprocessing route to develop a simple, one-pot bioprocess for the depolymerisation and biological conversion of bread waste into high-value compounds for use in the materials and pharmaceutical industries.

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How Studying Bacterial Evolution Could Help Us Fight Antibiotic Resistance

Antimicrobial resistance poses a critical global health threat, demanding new strategies beyond drug discovery. Hoskisson Lab's 3,000-generation evolution experiment with Streptomyces bacteria revealed that a single gene mutation drives faster growth and metabolic specialisation under industrial conditions - a finding that could accelerate the engineering of optimised antibiotic-producing strains and strengthen the pipeline against AMR.

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FlexBio, Downstream processing, Pharmaceuticals Valerie Evans FlexBio, Downstream processing, Pharmaceuticals Valerie Evans

Scaling Up Nucleotide Purification Using Preparative Chromatography

This collaboration enabled the successful tenfold scale-up of nucleotide purification for the University of St Andrews, demonstrating how IBioIC’s facilities and expertise can provide targeted scale-up services to academic partners bridging the gap between laboratory research and preparative bioprocessing.

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Microbial Synthesis of L‐DOPA from waste PET

Polyethelene terephthalate (PET) is a thermoplastic polymer resin which is used extensively across multiple industries including food and drink, pharmaceutical, cosmetics, and textiles.

Impact Solutions and the University of Edinburgh wanted to investigate the use of modern synthetic biology methods to design bacteria capable of transforming PET waste into the anti-Parkinson’s drug Levodopa (L-DOPA).

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Scale-up of Enzyme Production for Cyclodextrin Biomanufacturing

As part of their UKRI Launchpad project for Biomanufacturing in Scotland, NCIMB sought to transition their bench-scale process for producing the enzyme from static flask cultures to a controlled fermentation system suitable for larger-scale enzyme production. To enable this transition, NCIMB subcontracted the fermentation scale-up and enzyme recovery work to the Industrial Biotechnology Innovation Centre (IBioIC), leveraging the FlexBIO facility and technical expertise in bioprocess development and downstream processing.

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Food and drink, waste, Feedstock Steven Scott Food and drink, waste, Feedstock Steven Scott

Valorisation of co-products from the potato growing industry

Funding from IBioIC’s Feasibility Fund enabled Grampian Growers to work with Professor Giovanna Bermano from Robert Gordon University and Dr Gordon McDougall of The James Hutton Institute to assess the feasibility of valorising potato haulms as feedstocks for ingredients and high value products for global markets.

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